X-ray Irradiated Vaccine Confers protection against Pneumonia caused by Pseudomonas Aeruginosa
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X-ray Irradiated Vaccine Confers protection against Pneumonia caused by Pseudomonas Aeruginosa
Pseudomonas aeruginosa is a gram-negative bacterium and one of the leading causes of nosocomial infection worldwide, however, no effective vaccine is currently available in the market. Here, we demonstrate that inactivation of the bacteria by X-ray irradiation inhibits its replication capability but retained antigenic expression functionally thus allowing its use as a potential vaccine. Mice im...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep18823